Screening Clinical Cell Products for Replication Competent Retrovirus: The National Gene Vector Biorepository Experience

Replication-competent retrovirus (RCR) is a safety concern for individuals treated with retroviral gene therapy. RCR detection assays are used to detect RCR in manufactured vector, transduced cell products infused into research subjects, and in the research subjects after treatment. In this study, w...

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Detalhes bibliográficos
Publicado no:Mol Ther Methods Clin Dev
Main Authors: Cornetta, Kenneth, Duffy, Lisa, Feldman, Steven A., Mackall, Crystal L., Davila, Marco L., Curran, Kevin J., Junghans, Richard P., Tang, Jean Yuh, Kochenderfer, James N., O’Cearbhaill, Roisin, Archer, Gary, Kiem, Hans-Peter, Shah, Nirali N., Delbrook, Cindy, Kaplan, Rosie, Brentjens, Renier J., Rivière, Isabelle, Sadelain, Michel, Rosenberg, Steven A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6134358/
https://ncbi.nlm.nih.gov/pubmed/30211249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2018.08.006
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