Screening Clinical Cell Products for Replication Competent Retrovirus: The National Gene Vector Biorepository Experience

Replication-competent retrovirus (RCR) is a safety concern for individuals treated with retroviral gene therapy. RCR detection assays are used to detect RCR in manufactured vector, transduced cell products infused into research subjects, and in the research subjects after treatment. In this study, w...

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Bibliografiset tiedot
Julkaisussa:Mol Ther Methods Clin Dev
Päätekijät: Cornetta, Kenneth, Duffy, Lisa, Feldman, Steven A., Mackall, Crystal L., Davila, Marco L., Curran, Kevin J., Junghans, Richard P., Tang, Jean Yuh, Kochenderfer, James N., O’Cearbhaill, Roisin, Archer, Gary, Kiem, Hans-Peter, Shah, Nirali N., Delbrook, Cindy, Kaplan, Rosie, Brentjens, Renier J., Rivière, Isabelle, Sadelain, Michel, Rosenberg, Steven A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society of Gene & Cell Therapy 2018
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6134358/
https://ncbi.nlm.nih.gov/pubmed/30211249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2018.08.006
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