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PTEN loss and activation of K-RAS and β-catenin cooperate to accelerate prostate tumourigenesis
Aberrant phosphoinositide-3-kinase (PI3K), mitogen-activated protein kinase (MAPK) and WNT signalling are emerging as key events in the multistep nature of prostate tumourigenesis and progression. Here we report a compound prostate cancer murine model, in which these signalling pathways cooperate to...
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| Veröffentlicht in: | J Pathol |
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| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6128396/ https://ncbi.nlm.nih.gov/pubmed/29134654 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.4977 |
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