PTEN loss and activation of K-RAS and β-catenin cooperate to accelerate prostate tumourigenesis

Aberrant phosphoinositide-3-kinase (PI3K), mitogen-activated protein kinase (MAPK) and WNT signalling are emerging as key events in the multistep nature of prostate tumourigenesis and progression. Here we report a compound prostate cancer murine model, in which these signalling pathways cooperate to...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:J Pathol
Main Authors: Jefferies, Matthew T., Cox, Adam C., Shorning, Boris Y., Meniel, Valerie, Griffiths, David, Kynaston, Howard G., Smalley, Matthew J., Clarke, Alan R.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6128396/
https://ncbi.nlm.nih.gov/pubmed/29134654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.4977
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker