Llwytho...

ERRα suppression enhances the cytotoxicity of the MEK inhibitor trametinib against colon cancer cells

BACKGROUND: ERRα, a constitutive transcription factor that regulates energy metabolism, plays an important role in the progression of various tumours. However, its role in cell survival and proliferation and its implication in targeted therapy in colon cancer remains elusive. METHODS: The expression...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Exp Clin Cancer Res
Prif Awduron: Zhou, Sheng, Xia, Hongwei, Xu, Huanji, Tang, Qiulin, Nie, Yongzhan, Gong, Qi yong, Bi, Feng
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6125878/
https://ncbi.nlm.nih.gov/pubmed/30185207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-018-0862-8
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