ERRα suppression enhances the cytotoxicity of the MEK inhibitor trametinib against colon cancer cells

BACKGROUND: ERRα, a constitutive transcription factor that regulates energy metabolism, plays an important role in the progression of various tumours. However, its role in cell survival and proliferation and its implication in targeted therapy in colon cancer remains elusive. METHODS: The expression...

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Detaylı Bibliyografya
Yayımlandı:J Exp Clin Cancer Res
Asıl Yazarlar: Zhou, Sheng, Xia, Hongwei, Xu, Huanji, Tang, Qiulin, Nie, Yongzhan, Gong, Qi yong, Bi, Feng
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2018
Konular:
Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6125878/
https://ncbi.nlm.nih.gov/pubmed/30185207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-018-0862-8
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