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Targeting SERT promotes tryptophan metabolism: mechanisms and implications in colon cancer treatment

BACKGROUND: Serotonin signaling has been associated with tumorigenesis and tumor progression. Targeting the serotonin transporter to block serotonin cellular uptake confers antineoplastic effects in various tumors, including colon cancer. However, the antineoplastic mechanism of serotonin transporte...

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Bibliografische gegevens
Gepubliceerd in:J Exp Clin Cancer Res
Hoofdauteurs: Ye, Di, Xu, Huanji, Xia, Hongwei, Zhang, Chenliang, Tang, Qiulin, Bi, Feng
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2021
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8132442/
https://ncbi.nlm.nih.gov/pubmed/34006301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-021-01971-1
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