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ERRα suppression enhances the cytotoxicity of the MEK inhibitor trametinib against colon cancer cells
BACKGROUND: ERRα, a constitutive transcription factor that regulates energy metabolism, plays an important role in the progression of various tumours. However, its role in cell survival and proliferation and its implication in targeted therapy in colon cancer remains elusive. METHODS: The expression...
Sparad:
| I publikationen: | J Exp Clin Cancer Res |
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| Huvudupphovsmän: | , , , , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
BioMed Central
2018
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6125878/ https://ncbi.nlm.nih.gov/pubmed/30185207 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-018-0862-8 |
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