Inhibition of ISG15 Enhances the Anti-Cancer Effect of Trametinib in Colon Cancer Cells

BACKGROUND: Colon cancer is one of the most common cancers worldwide. IFN-stimulated gene 15 (ISG15), a ubiquitin-like molecule, is strongly up-regulated by type I interferon as a crucial response to a variety of microbial and cellular stress stimuli. However, the role of ISG15 in colon cancer remai...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Onco Targets Ther
Egile Nagusiak: Zhou, Sheng, Ren, Meilin, Xu, Huanji, Xia, Hongwei, Tang, Qiulin, Liu, Ming
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Dove 2019
Gaiak:
Original Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6884973/
https://ncbi.nlm.nih.gov/pubmed/32063716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S226395
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