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Frequent mutation of the FOXA1 untranslated region in prostate cancer
Prostate cancer has a low somatic mutation rate but non-coding regions remain underexplored. We sequenced the untranslated regions (UTRs) of 72 established driver genes in 428 patients with metastatic prostate cancer and identified FOXA1 3′-UTR mutations in 12% of patients. The mutations were predom...
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| Publicado no: | Commun Biol |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6123809/ https://ncbi.nlm.nih.gov/pubmed/30272002 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-018-0128-1 |
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