Genomic alterations in cell-free DNA and enzalutamide resistance in castration-resistant prostate cancer

IMPORTANCE: The molecular landscape underpinning response to the androgen receptor (AR) antagonist enzalutamide in metastatic castration-resistant prostate cancer (mCRPC) patients is undefined. Consequently, there is an urgent need for practical biomarkers to guide therapy selection and understand r...

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Detalhes bibliográficos
Publicado no:JAMA Oncol
Main Authors: Wyatt, Alexander W, Azad, Arun A, Volik, Stanislav V, Annala, Matti, Beja, Kevin, McConeghy, Brian, Haegert, Anne, Warner, Evan W, Mo, Fan, Brahmbhatt, Sonal, Shukin, Robert, Le Bihan, Stephane, Gleave, Martin E, Nykter, Matti, Collins, Colin C, Chi, Kim N
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5097690/
https://ncbi.nlm.nih.gov/pubmed/27148695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaoncol.2016.0494
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