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Targeting the adaptive molecular landscape of castration-resistant prostate cancer

Castration and androgen receptor (AR) pathway inhibitors induce profound and sustained responses in advanced prostate cancer. However, the inevitable recurrence is associated with reactivation of the AR and progression to a more aggressive phenotype termed castration-resistant prostate cancer (CRPC)...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:EMBO Mol Med
Hauptverfasser: Wyatt, Alexander W, Gleave, Martin E
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley & Sons, Ltd 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4520654/
https://ncbi.nlm.nih.gov/pubmed/25896606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201303701
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