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Targeting the adaptive molecular landscape of castration-resistant prostate cancer

Castration and androgen receptor (AR) pathway inhibitors induce profound and sustained responses in advanced prostate cancer. However, the inevitable recurrence is associated with reactivation of the AR and progression to a more aggressive phenotype termed castration-resistant prostate cancer (CRPC)...

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Detalhes bibliográficos
Publicado no:EMBO Mol Med
Main Authors: Wyatt, Alexander W, Gleave, Martin E
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4520654/
https://ncbi.nlm.nih.gov/pubmed/25896606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201303701
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