Genomic alterations in cell-free DNA and enzalutamide resistance in castration-resistant prostate cancer

IMPORTANCE: The molecular landscape underpinning response to the androgen receptor (AR) antagonist enzalutamide in metastatic castration-resistant prostate cancer (mCRPC) patients is undefined. Consequently, there is an urgent need for practical biomarkers to guide therapy selection and understand r...

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Bibliografiset tiedot
Julkaisussa:JAMA Oncol
Päätekijät: Wyatt, Alexander W, Azad, Arun A, Volik, Stanislav V, Annala, Matti, Beja, Kevin, McConeghy, Brian, Haegert, Anne, Warner, Evan W, Mo, Fan, Brahmbhatt, Sonal, Shukin, Robert, Le Bihan, Stephane, Gleave, Martin E, Nykter, Matti, Collins, Colin C, Chi, Kim N
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2016
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5097690/
https://ncbi.nlm.nih.gov/pubmed/27148695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaoncol.2016.0494
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