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Frequent FOXA1-Activating Mutations in Extramammary Paget’s Disease
Extramammary Paget’s disease (EMPD) is a neoplastic skin disease of indeterminate origin with an unknown genetic cause. We performed a comprehensive genetic analysis or targeted gene sequencing in 48 patients with EMPD. We identified FOXA1 mutations, a GAS6–FOXA1 fusion gene, and somatic hotspot mut...
Gardado en:
| Publicado en: | Cancers (Basel) |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
MDPI
2020
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7226542/ https://ncbi.nlm.nih.gov/pubmed/32235312 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12040820 |
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