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Cigarette Smoke Induces Stem Cell Features of Pancreatic Cancer Cells via PAF1

BACKGROUND & AIMS: Cigarette smoking is a major risk factor for pancreatic cancer. Aggressive pancreatic tumors contain cancer cells with stem cell features. We investigated whether cigarette smoke induces stem cell features in pancreatic cancer cells. METHODS: Kras(G12D); Pdx1-Cre (KC) mice wer...

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Bibliografiset tiedot
Julkaisussa:Gastroenterology
Päätekijät: Nimmakayala, Rama Krishna, Seshacharyulu, Parthasarathy, Lakshmanan, Imayavaramban, Rachagani, Satyanarayana, Chugh, Seema, Karmakar, Saswati, Rauth, Sanchita, Vengoji, Raghupathy, Atri, Pranita, Talmon, Geoffrey A., Lele, Subodh M., Smith, Lynette M., Thapa, Ishwor, Bastola, Dhundy, Ouellette, Michel M., Batra, Surinder K., Ponnusamy, Moorthy P.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2018
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6120776/
https://ncbi.nlm.nih.gov/pubmed/29864419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2018.05.041
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