MicroRNA Regulation of K-Ras in Pancreatic Cancer and Opportunities for Therapeutic Intervention

The Ras family of GTPases is involved in cell proliferation, cell survival, and angiogenesis. It is upregulated in several cancers, including pancreatic cancer (PC) and leads to uncontrolled growth and aggressiveness. PC is well known to be a lethal disease with poor prognosis, plagued by limited th...

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Bibliographic Details
Published in:Semin Cancer Biol
Main Authors: Karmakar, Saswati, Kaushik, Garima, Nimmakayala, Ramakrishna, Rachagani, Satyanarayana, Ponnusamy, Moorthy P., Batra, Surinder K.
Format: Artigo
Language:Inglês
Published: 2017
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5984665/
https://ncbi.nlm.nih.gov/pubmed/29199014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcancer.2017.11.020
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