Novel role of O-glycosyltransferases GALNT3 and B3GNT3 in the self-renewal of pancreatic cancer stem cells

BACKGROUND: Glycosylation plays a critical role in the aggressiveness of pancreatic cancer (PC). Emerging evidences indicate significant involvement of cancer stem cells (CSCs) in PC aggressiveness. However, the importance of glycosylation in pancreatic cancer stem cells (PCSCs) is yet to be address...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Barkeer, Srikanth, Chugh, Seema, Karmakar, Saswati, Kaushik, Garima, Rauth, Sanchita, Rachagani, Satyanarayana, Batra, Surinder K., Ponnusamy, Moorthy P.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6251200/
https://ncbi.nlm.nih.gov/pubmed/30466404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-018-5074-2
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