Global analysis of human glycosyltransferases reveals novel targets for pancreatic cancer pathogenesis

BACKGROUND: Several reports have shown the role of glycosylation in pancreatic cancer (PC), but a global systematic screening of specific glycosyltransferases (glycoTs) in its progression remains unknown. METHODS: We demonstrate a rigorous top-down approach using TCGA-based RNA-Seq analysis, multi-s...

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Pubblicato in:Br J Cancer
Autori principali: Gupta, Rohitesh, Leon, Frank, Thompson, Christopher M., Nimmakayala, Ramakrishna, Karmakar, Saswati, Nallasamy, Palanisamy, Chugh, Seema, Prajapati, Dipakkumar R., Rachagani, Satyanarayana, Kumar, Sushil, Ponnusamy, Moorthy P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7251111/
https://ncbi.nlm.nih.gov/pubmed/32203219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-020-0772-3
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