Cigarette Smoke Induces Stem Cell Features of Pancreatic Cancer Cells via PAF1

BACKGROUND & AIMS: Cigarette smoking is a major risk factor for pancreatic cancer. Aggressive pancreatic tumors contain cancer cells with stem cell features. We investigated whether cigarette smoke induces stem cell features in pancreatic cancer cells. METHODS: Kras(G12D); Pdx1-Cre (KC) mice wer...

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Publicado no:Gastroenterology
Main Authors: Nimmakayala, Rama Krishna, Seshacharyulu, Parthasarathy, Lakshmanan, Imayavaramban, Rachagani, Satyanarayana, Chugh, Seema, Karmakar, Saswati, Rauth, Sanchita, Vengoji, Raghupathy, Atri, Pranita, Talmon, Geoffrey A., Lele, Subodh M., Smith, Lynette M., Thapa, Ishwor, Bastola, Dhundy, Ouellette, Michel M., Batra, Surinder K., Ponnusamy, Moorthy P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6120776/
https://ncbi.nlm.nih.gov/pubmed/29864419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2018.05.041
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