Cigarette Smoke Induces Stem Cell Features of Pancreatic Cancer Cells via PAF1

BACKGROUND & AIMS: Cigarette smoking is a major risk factor for pancreatic cancer. Aggressive pancreatic tumors contain cancer cells with stem cell features. We investigated whether cigarette smoke induces stem cell features in pancreatic cancer cells. METHODS: Kras(G12D); Pdx1-Cre (KC) mice wer...

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Udgivet i:Gastroenterology
Main Authors: Nimmakayala, Rama Krishna, Seshacharyulu, Parthasarathy, Lakshmanan, Imayavaramban, Rachagani, Satyanarayana, Chugh, Seema, Karmakar, Saswati, Rauth, Sanchita, Vengoji, Raghupathy, Atri, Pranita, Talmon, Geoffrey A., Lele, Subodh M., Smith, Lynette M., Thapa, Ishwor, Bastola, Dhundy, Ouellette, Michel M., Batra, Surinder K., Ponnusamy, Moorthy P.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6120776/
https://ncbi.nlm.nih.gov/pubmed/29864419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2018.05.041
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