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Whole-genome bisulfite sequencing with improved accuracy and cost

DNA methylation patterns in the genome both reflect and help to mediate transcriptional regulatory processes. The digital nature of DNA methylation, present or absent on each allele, makes this assay capable of quantifying events in subpopulations of cells, whereas genome-wide chromatin studies lack...

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Publicat a:Genome Res
Autors principals: Suzuki, Masako, Liao, Will, Wos, Frank, Johnston, Andrew D., DeGrazia, Justin, Ishii, Jennifer, Bloom, Toby, Zody, Michael C., Germer, Soren, Greally, John M.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6120621/
https://ncbi.nlm.nih.gov/pubmed/30093547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.232587.117
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