Statistically robust methylation calling for whole-transcriptome bisulfite sequencing reveals distinct methylation patterns for mouse RNAs

Cytosine-5 RNA methylation plays an important role in several biologically and pathologically relevant processes. However, owing to methodological limitations, the transcriptome-wide distribution of this mark has remained largely unknown. We previously established RNA bisulfite sequencing as a metho...

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Detalhes bibliográficos
Publicado no:Genome Res
Main Authors: Legrand, Carine, Tuorto, Francesca, Hartmann, Mark, Liebers, Reinhard, Jacob, Dominik, Helm, Mark, Lyko, Frank
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2017
Assuntos:
Method
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5580717/
https://ncbi.nlm.nih.gov/pubmed/28684555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.210666.116
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