Queuosine‐modified tRNAs confer nutritional control of protein translation

Global protein translation as well as translation at the codon level can be regulated by tRNA modifications. In eukaryotes, levels of tRNA queuosinylation reflect the bioavailability of the precursor queuine, which is salvaged from the diet and gut microbiota. We show here that nutritionally determi...

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Pubblicato in:EMBO J
Autori principali: Tuorto, Francesca, Legrand, Carine, Cirzi, Cansu, Federico, Giuseppina, Liebers, Reinhard, Müller, Martin, Ehrenhofer‐Murray, Ann E, Dittmar, Gunnar, Gröne, Hermann‐Josef, Lyko, Frank
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2018
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6138434/
https://ncbi.nlm.nih.gov/pubmed/30093495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201899777
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