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The tRNA methyltransferase Dnmt2 is required for accurate polypeptide synthesis during haematopoiesis
The Dnmt2 enzyme utilizes the catalytic mechanism of eukaryotic DNA methyltransferases to methylate several tRNAs at cytosine 38. Dnmt2 mutant mice, flies, and plants were reported to be viable and fertile, and the biological function of Dnmt2 has remained elusive. Here, we show that endochondral os...
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| 出版年: | EMBO J |
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| 主要な著者: | , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
John Wiley & Sons, Ltd
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4570521/ https://ncbi.nlm.nih.gov/pubmed/26271101 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201591382 |
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