The tRNA methyltransferase Dnmt2 is required for accurate polypeptide synthesis during haematopoiesis

The Dnmt2 enzyme utilizes the catalytic mechanism of eukaryotic DNA methyltransferases to methylate several tRNAs at cytosine 38. Dnmt2 mutant mice, flies, and plants were reported to be viable and fertile, and the biological function of Dnmt2 has remained elusive. Here, we show that endochondral os...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :EMBO J
Главные авторы: Tuorto, Francesca, Herbst, Friederike, Alerasool, Nader, Bender, Sebastian, Popp, Oliver, Federico, Giuseppina, Reitter, Sonja, Liebers, Reinhard, Stoecklin, Georg, Gröne, Hermann-Josef, Dittmar, Gunnar, Glimm, Hanno, Lyko, Frank
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley & Sons, Ltd 2015
Предметы:
Articles
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4570521/
https://ncbi.nlm.nih.gov/pubmed/26271101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201591382
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы