Epigenetic Guardian: A Review of the DNA Methyltransferase DNMT3A in Acute Myeloid Leukaemia and Clonal Haematopoiesis

Acute myeloid leukaemia (AML) is a haematological malignancy characterized by clonal stem cell proliferation and aberrant block in differentiation. Dysfunction of epigenetic modifiers contributes significantly to the pathogenesis of AML. One frequently mutated gene involved in epigenetic modificatio...

Full description

Saved in:
Bibliographic Details
Published in:Biomed Res Int
Main Authors: Chaudry, Sabah F., Chevassut, Timothy J. T.
Format: Artigo
Language:Inglês
Published: Hindawi Publishing Corporation 2017
Subjects:
Review Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5329657/
https://ncbi.nlm.nih.gov/pubmed/28286768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/5473197
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items