Efficient RNA virus control in Drosophila requires the RNA methyltransferase Dnmt2

Drosophila use small-interfering RNA mechanisms to limit the amplification of viral genomes. However, it is unclear how small RNA interference components recognize and separate viral from cellular RNA. Dnmt2 enzymes are highly conserved RNA methyltransferases with substrate specificity towards cellu...

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Bibliographic Details
Main Authors: Durdevic, Zeljko, Hanna, Katharina, Gold, Beth, Pollex, Tim, Cherry, Sara, Lyko, Frank, Schaefer, Matthias
Format: Artigo
Language:Inglês
Published: European Molecular Biology Organization 2013
Subjects:
Scientific Reports
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3589093/
https://ncbi.nlm.nih.gov/pubmed/23370384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2013.3
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