Queuosine‐modified tRNAs confer nutritional control of protein translation

Global protein translation as well as translation at the codon level can be regulated by tRNA modifications. In eukaryotes, levels of tRNA queuosinylation reflect the bioavailability of the precursor queuine, which is salvaged from the diet and gut microbiota. We show here that nutritionally determi...

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Bibliographic Details
Published in:EMBO J
Main Authors: Tuorto, Francesca, Legrand, Carine, Cirzi, Cansu, Federico, Giuseppina, Liebers, Reinhard, Müller, Martin, Ehrenhofer‐Murray, Ann E, Dittmar, Gunnar, Gröne, Hermann‐Josef, Lyko, Frank
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6138434/
https://ncbi.nlm.nih.gov/pubmed/30093495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201899777
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