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Amplification-free whole-genome bisulfite sequencing by post-bisulfite adaptor tagging
DNA methylation plays a key role in epigenetic regulation of eukaryotic genomes. Hence the genome-wide distribution of 5-methylcytosine, or the methylome, has been attracting intense attention. In recent years, whole-genome bisulfite sequencing (WGBS) has enabled methylome analysis at single-base re...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3458524/ https://ncbi.nlm.nih.gov/pubmed/22649061 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks454 |
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