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Amplification-free whole-genome bisulfite sequencing by post-bisulfite adaptor tagging

DNA methylation plays a key role in epigenetic regulation of eukaryotic genomes. Hence the genome-wide distribution of 5-methylcytosine, or the methylome, has been attracting intense attention. In recent years, whole-genome bisulfite sequencing (WGBS) has enabled methylome analysis at single-base re...

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Библиографические подробности
Главные авторы: Miura, Fumihito, Enomoto, Yusuke, Dairiki, Ryo, Ito, Takashi
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2012
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3458524/
https://ncbi.nlm.nih.gov/pubmed/22649061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks454
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