Comparison and quantitative verification of mapping algorithms for whole-genome bisulfite sequencing

Coupling bisulfite conversion with next-generation sequencing (Bisulfite-seq) enables genome-wide measurement of DNA methylation, but poses unique challenges for mapping. However, despite a proliferation of Bisulfite-seq mapping tools, no systematic comparison of their genomic coverage and quantitat...

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Bibliografiska uppgifter
Huvudupphovsmän: Kunde-Ramamoorthy, Govindarajan, Coarfa, Cristian, Laritsky, Eleonora, Kessler, Noah J., Harris, R. Alan, Xu, Mingchu, Chen, Rui, Shen, Lanlan, Milosavljevic, Aleksandar, Waterland, Robert A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2014
Ämnen:
Methods Online
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3973287/
https://ncbi.nlm.nih.gov/pubmed/24391148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt1325
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