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Identification of cell type-specific methylation signals in bulk whole genome bisulfite sequencing data

BACKGROUND: The traditional approach to studying the epigenetic mechanism CpG methylation in tissue samples is to identify regions of concordant differential methylation spanning multiple CpG sites (differentially methylated regions). Variation limited to single or small numbers of CpGs has been ass...

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Detalhes bibliográficos
Publicado no:Genome Biol
Main Authors: Scott, C. Anthony, Duryea, Jack D., MacKay, Harry, Baker, Maria S., Laritsky, Eleonora, Gunasekara, Chathura J., Coarfa, Cristian, Waterland, Robert A.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7329512/
https://ncbi.nlm.nih.gov/pubmed/32605651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-020-02065-5
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