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Identification of cell type-specific methylation signals in bulk whole genome bisulfite sequencing data

BACKGROUND: The traditional approach to studying the epigenetic mechanism CpG methylation in tissue samples is to identify regions of concordant differential methylation spanning multiple CpG sites (differentially methylated regions). Variation limited to single or small numbers of CpGs has been ass...

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書誌詳細
出版年:Genome Biol
主要な著者: Scott, C. Anthony, Duryea, Jack D., MacKay, Harry, Baker, Maria S., Laritsky, Eleonora, Gunasekara, Chathura J., Coarfa, Cristian, Waterland, Robert A.
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7329512/
https://ncbi.nlm.nih.gov/pubmed/32605651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-020-02065-5
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