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Ultra-low-input, tagmentation-based whole-genome bisulfite sequencing
We have adapted transposase-based in vitro shotgun library construction (“tagmentation”) for whole-genome bisulfite sequencing. This method, Tn5mC-seq, enables a >100-fold reduction in starting material relative to conventional protocols, such that we generate highly complex bisulfite sequencing...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2012
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3371708/ https://ncbi.nlm.nih.gov/pubmed/22466172 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.136242.111 |
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