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Increased Sensitivity in Whole-Genome Bisulfite Sequencing (Wgbs): A Novel “Post-bisulfite Conversion” Library Construction Method from Sub-nanogram DNA Inputs
Genome-wide analysis of 5-methylcytosines is possible with whole-genome bisulfite sequencing (WGBS), where unmethylated cytosine residues are converted to uracil. However, a major challenge in WGBS is the degradation of DNA that occurs during bisulfite conversion under conditions required for comple...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Association of Biomolecular Resource Facilities
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3635258/ |
| タグ: |
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