Increased Sensitivity in Whole-Genome Bisulfite Sequencing (Wgbs): A Novel “Post-bisulfite Conversion” Library Construction Method from Sub-nanogram DNA Inputs

Genome-wide analysis of 5-methylcytosines is possible with whole-genome bisulfite sequencing (WGBS), where unmethylated cytosine residues are converted to uracil. However, a major challenge in WGBS is the degradation of DNA that occurs during bisulfite conversion under conditions required for comple...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Hitchen, John, Gabel, Dixie, Caruccio, Nick, Adey, Andrew, Sooknanan, Roy
التنسيق: Artigo
اللغة:Inglês
منشور في: Association of Biomolecular Resource Facilities 2013
الموضوعات:
Poster Session Abstracts
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC3635258/
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