Information recovery from low coverage whole-genome bisulfite sequencing

The cost of whole-genome bisulfite sequencing (WGBS) remains a bottleneck for many studies and it is therefore imperative to extract as much information as possible from a given dataset. This is particularly important because even at the recommend 30X coverage for reference methylomes, up to 50% of...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Libertini, Emanuele, Heath, Simon C., Hamoudi, Rifat A., Gut, Marta, Ziller, Michael J., Czyz, Agata, Ruotti, Victor, Stunnenberg, Hendrik G., Frontini, Mattia, Ouwehand, Willem H., Meissner, Alexander, Gut, Ivo G., Beck, Stephan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4931220/
https://ncbi.nlm.nih.gov/pubmed/27346250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11306
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