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Coverage recommendations for methylation analysis by whole genome bisulfite sequencing
Whole genome bisulfite sequencing (WGBS) allows genome-wide DNA methylation profiling but the associated high sequencing costs continue to limit its widespread application. We utilized several high coverage reference data sets to experimentally determine minimal sequencing requirements. Here, we pre...
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| Publicado en: | Nat Methods |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4344394/ https://ncbi.nlm.nih.gov/pubmed/25362363 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.3152 |
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