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Coverage recommendations for methylation analysis by whole genome bisulfite sequencing
Whole genome bisulfite sequencing (WGBS) allows genome-wide DNA methylation profiling but the associated high sequencing costs continue to limit its widespread application. We utilized several high coverage reference data sets to experimentally determine minimal sequencing requirements. Here, we pre...
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| Publicado en: | Nat Methods |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2014
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4344394/ https://ncbi.nlm.nih.gov/pubmed/25362363 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.3152 |
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