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Cancer Drug Development of Carbonic Anhydrase Inhibitors beyond the Active Site
Carbonic anhydrases (CAs) catalyze the reversible hydration of carbon dioxide to produce bicarbonate and a proton. Multiple CA isoforms are implicated in a range of diseases, including cancer. In solid tumors, continuously dividing cells create hypoxic conditions that eventually lead to an acidic mi...
Shranjeno v:
| izdano v: | Molecules |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
MDPI
2018
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6099549/ https://ncbi.nlm.nih.gov/pubmed/29710858 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23051045 |
| Oznake: |
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