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Carbonic anhydrase II in complex with carboxylic acid-based inhibitors

Carbonic anhydrases (CAs) are molecular targets in various diseases. While many sulfonamide-based drugs are in clinical use, CA inhibitor design is moving towards the incorporation of alternative zinc-binding groups, such as carboxylic acids, to promote CA isoform-specific inhibition. Here, X-ray cr...

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Detaylı Bibliyografya
Yayımlandı:Acta Crystallogr F Struct Biol Commun
Asıl Yazarlar: Lomelino, Carrie L., McKenna, Robert
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: International Union of Crystallography 2019
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6404860/
https://ncbi.nlm.nih.gov/pubmed/30839290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X18018344
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