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Carbonic anhydrase II in complex with carboxylic acid-based inhibitors
Carbonic anhydrases (CAs) are molecular targets in various diseases. While many sulfonamide-based drugs are in clinical use, CA inhibitor design is moving towards the incorporation of alternative zinc-binding groups, such as carboxylic acids, to promote CA isoform-specific inhibition. Here, X-ray cr...
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| Publicado en: | Acta Crystallogr F Struct Biol Commun |
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| Autores principales: | , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
International Union of Crystallography
2019
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6404860/ https://ncbi.nlm.nih.gov/pubmed/30839290 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X18018344 |
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