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Human carbonic anhydrase II–cyanate inhibitor complex: putting the debate to rest

The binding of anions to carbonic anhydrase II (CA II) has been attributed to high affinity for the active-site zinc. An anion of interest is cyanate, for which contrasting binding modes have been reported in the literature. Previous spectroscopic data have shown cyanate behaving as an inhibitor, di...

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Detalhes bibliográficos
Main Authors: West, Dayne, Pinard, Melissa A., Tu, Chingkuang, Silverman, David N., McKenna, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4188073/
https://ncbi.nlm.nih.gov/pubmed/25286933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X14018135
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