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Probing the Surface of Human Carbonic Anhydrase for Clues towards the Design of Isoform Specific Inhibitors
The alpha carbonic anhydrases (α-CAs) are a group of structurally related zinc metalloenzymes that catalyze the reversible hydration of CO(2) to HCO(3) (−). Humans have 15 different α-CAs with numerous physiological roles and expression patterns. Of these, 12 are catalytically active, and abnormal e...
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| Publicado no: | Biomed Res Int |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Hindawi Publishing Corporation
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4355338/ https://ncbi.nlm.nih.gov/pubmed/25811028 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/453543 |
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