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Targeting Carbonic Anhydrase IX Activity and Expression
Metastatic tumors are often hypoxic exhibiting a decrease in extracellular pH (~6.5) due to a metabolic transition described by the Warburg Effect. This shift in tumor cell metabolism alters the tumor milieu inducing tumor cell proliferation, angiogenesis, cell motility, invasiveness, and often resi...
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| Publié dans: | Molecules |
|---|---|
| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
MDPI
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6272707/ https://ncbi.nlm.nih.gov/pubmed/25647573 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules20022323 |
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