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Location of Binding Sites in Small Molecule Rescue of Human Carbonic Anhydrase II

Small molecule rescue of mutant forms of human carbonic anhydrase II (HCA II) occurs by participation of exogenous donors/acceptors in the proton transfer pathway between the zinc-bound water and solution. To examine more thoroughly the energetics of this activation, we have constructed a mutant, H6...

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Bibliografiset tiedot
Päätekijät: Bhatt, Deepa, Fisher, S. Zoë, Tu, Chingkuang, McKenna, Robert, Silverman, David N.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Biophysical Society 2007
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1751391/
https://ncbi.nlm.nih.gov/pubmed/17071654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.093203
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