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Carbonic Anhydrases: Role in pH Control and Cancer

The pH of the tumor microenvironment drives the metastatic phenotype and chemotherapeutic resistance of tumors. Understanding the mechanisms underlying this pH-dependent phenomenon will lead to improved drug delivery and allow the identification of new therapeutic targets. This includes an understan...

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Bibliographic Details
Published in:Metabolites
Main Authors: Mboge, Mam Y., Mahon, Brian P., McKenna, Robert, Frost, Susan C.
Format: Artigo
Language:Inglês
Published: MDPI 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5876008/
https://ncbi.nlm.nih.gov/pubmed/29495652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/metabo8010019
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