載入...
Rigid Peptide Macrocycles via On-Resin Glaser Stapling
Peptide macrocycles are widely utilized in the development of high affinity ligands including stapled α-helices. The linear rigidity of a 1,3-diynyl linkage provides an optimal distance (7 Å) between β- carbons of the i, i+4 amino acid side chains, suggesting its utility in stabilizing α-helical str...
Na minha lista:
| 發表在: | Chembiochem |
|---|---|
| Main Authors: | , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2018
|
| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6097620/ https://ncbi.nlm.nih.gov/pubmed/29516601 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201800121 |
| 標簽: |
添加標簽
沒有標簽, 成為第一個標記此記錄!
|