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ACE-linked peptides: a convergent approach for peptide macrocyclization and labeling

Macrocyclization is a broadly applied approach for overcoming the intrinsically disordered nature of linear peptides. For example, significant efforts have been developed to stabilize α-helical structures, through tethering proximal side chains. While these approaches successfully mimic protein α-he...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Assem, Naila, Ferreira, David J., Wolan, Dennis W., Dawson, Philip E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4824200/
https://ncbi.nlm.nih.gov/pubmed/26096515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201502607
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