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Long Noncoding RNA ITPRIP-1 Positively Regulates the Innate Immune Response through Promotion of Oligomerization and Activation of MDA5

Emerging evidence indicates that long noncoding RNAs (lncRNAs) regulate various biological processes, especially innate and adaptive immunity. However, the relationship between lncRNAs and the interferon (IFN) pathway remains largely unknown. Here, we report that lncRNA ITPRIP-1 (lncITPRIP-1) is inv...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Xie, Qinya, Chen, Shengwen, Tian, Renyun, Huang, Xiang, Deng, Rilin, Xue, Binbin, Qin, Yuwen, Xu, Yan, Wang, Jingjing, Guo, Mengmeng, Chen, Jinwen, Tang, Songqing, Li, Guangdi, Zhu, Haizhen
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6096792/
https://ncbi.nlm.nih.gov/pubmed/29899107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00507-18
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