Long Noncoding RNA ITPRIP-1 Positively Regulates the Innate Immune Response through Promotion of Oligomerization and Activation of MDA5

Emerging evidence indicates that long noncoding RNAs (lncRNAs) regulate various biological processes, especially innate and adaptive immunity. However, the relationship between lncRNAs and the interferon (IFN) pathway remains largely unknown. Here, we report that lncRNA ITPRIP-1 (lncITPRIP-1) is inv...

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Библиографические подробности
Опубликовано в: :J Virol
Главные авторы: Xie, Qinya, Chen, Shengwen, Tian, Renyun, Huang, Xiang, Deng, Rilin, Xue, Binbin, Qin, Yuwen, Xu, Yan, Wang, Jingjing, Guo, Mengmeng, Chen, Jinwen, Tang, Songqing, Li, Guangdi, Zhu, Haizhen
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2018
Предметы:
Pathogenesis and Immunity
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6096792/
https://ncbi.nlm.nih.gov/pubmed/29899107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00507-18
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