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IRF1 Promotes the Innate Immune Response to Viral Infection by Enhancing the Activation of IRF3

Innate immunity is an essential way for host cells to resist viral infection through the production of interferons (IFNs) and proinflammatory cytokines. Interferon regulatory factor 3 (IRF3) plays a critical role in the innate immune response to viral infection. However, the role of IRF1 in innate i...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Wang, Jingjing, Li, Huiyi, Xue, Binbin, Deng, Rilin, Huang, Xiang, Xu, Yan, Chen, Shengwen, Tian, Renyun, Wang, Xintao, Xun, Zhen, Sang, Ming, Zhu, Haizhen
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7592201/
https://ncbi.nlm.nih.gov/pubmed/32878885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01231-20
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