Long Noncoding RNA ITPRIP-1 Positively Regulates the Innate Immune Response through Promotion of Oligomerization and Activation of MDA5

Emerging evidence indicates that long noncoding RNAs (lncRNAs) regulate various biological processes, especially innate and adaptive immunity. However, the relationship between lncRNAs and the interferon (IFN) pathway remains largely unknown. Here, we report that lncRNA ITPRIP-1 (lncITPRIP-1) is inv...

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Bibliographische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Xie, Qinya, Chen, Shengwen, Tian, Renyun, Huang, Xiang, Deng, Rilin, Xue, Binbin, Qin, Yuwen, Xu, Yan, Wang, Jingjing, Guo, Mengmeng, Chen, Jinwen, Tang, Songqing, Li, Guangdi, Zhu, Haizhen
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2018
Schlagworte:
Pathogenesis and Immunity
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6096792/
https://ncbi.nlm.nih.gov/pubmed/29899107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00507-18
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