Long Noncoding RNA ITPRIP-1 Positively Regulates the Innate Immune Response through Promotion of Oligomerization and Activation of MDA5

Emerging evidence indicates that long noncoding RNAs (lncRNAs) regulate various biological processes, especially innate and adaptive immunity. However, the relationship between lncRNAs and the interferon (IFN) pathway remains largely unknown. Here, we report that lncRNA ITPRIP-1 (lncITPRIP-1) is inv...

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Gepubliceerd in:J Virol
Hoofdauteurs: Xie, Qinya, Chen, Shengwen, Tian, Renyun, Huang, Xiang, Deng, Rilin, Xue, Binbin, Qin, Yuwen, Xu, Yan, Wang, Jingjing, Guo, Mengmeng, Chen, Jinwen, Tang, Songqing, Li, Guangdi, Zhu, Haizhen
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2018
Onderwerpen:
Pathogenesis and Immunity
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6096792/
https://ncbi.nlm.nih.gov/pubmed/29899107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00507-18
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