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Probing hyper-negatively supercoiled mini-circles with nucleases and DNA binding proteins

It is well accepted that the introduction of negative supercoils locally unwinds the DNA double helix, influencing thus the activity of proteins. Despite the use of recent methods of molecular dynamics simulations to model the DNA supercoiling-induced DNA deformation, the precise extent and location...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS One
Prif Awduron: Saintomé, Carole, Delagoutte, Emmanuelle
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6095550/
https://ncbi.nlm.nih.gov/pubmed/30114256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0202138
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