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Cascade-mediated binding and bending of negatively supercoiled DNA
Prokaryotes possess various defense mechanisms against invading DNA. Adaptive defense by CRISPR/Cas relies on incorporation of invader DNA sequences in the host genome. In Escherichia coli, processed transcripts of these incorporated sequences (crRNAs) guide Cascade-mediated invader DNA recognition....
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Landes Bioscience
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3579878/ https://ncbi.nlm.nih.gov/pubmed/22954644 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/rna.21410 |
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